[Answered]: Your patient is a 32 year old man with spasticity…

Your patient is a 32 year old man with spasticity caused by a spinal cord injury. His spasticity can be controlled somewhat by high doses of oral baclofen, but this treatment causes excessive sedation. When discussing this problem with the patient and his physician, you should suggest that baclofen could be administered orally with other drugs that increase GABA function in the CNS orally with other drugs that inhibit GABA function in the CNS directly into the blood stream by an intravenous pump directly into the subarachnoid space by a baclofen pump