[Answered]: HP is a 23-year-old woman who works as a toll…

HP is a 23-year-old woman who works as a toll taker at the Bay Bridge tunnel. She complains of constant thirst, frequent urination, and the loss of almost 30 lb in the last month in spite of her continued good appetite. She likes to bake cookies and shares them daily with her fellow toll takers. HP has been obese from adolescence and suffers from Crohn disease; her mild hypertension is being controlled with propranolol (Betachron E-R, 80 mg q.d.; structure #1). A random serum glucose determination yielded a value of 150 mg/dL (normal 70–110 mg/dL). Her serum insulin was 67 μIU/mL (normal 5–15 μIU/mL). A seven-unit insulin challenge produced no effect on serum glucose levels. All clinical signs indicate type 2 diabetes mellitus. Evaluate the structures and select an appropriate therapy for HP.